Monday, February 3, 2025

A protein at the heart of heart disease

Low-density lipoproteins (LDL) -- commonly known as bad cholesterol -- have long been on scientists' radar as a major contributor to heart disease. But these microscopic troublemakers have hidden their inner workings behind a maze of complexity. That is, until now. Researchers have now revealed the specific shape and structure of one of the body's most important yet complicated proteins: ApoB100. Acting as a kind of molecular exoskeleton, this protein wraps around LDL particles, allowing them to travel through the bloodstream, researchers found.

from Top Health News -- ScienceDaily https://ift.tt/StKVCNq

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Scientists found a new Alzheimer’s trigger and a drug that stops it

Researchers have identified a new Alzheimer’s target and created an experimental compound that blocks a damaging process inside brain cells....