Wednesday, August 31, 2022

Sex differences and AFib: New study flips conventional wisdom

New research has found women -- when height is accounted for -- have a 50% higher risk of developing the abnormal heart rhythm disturbance when compared to men.

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The shape of coronavirus affects its transmission, finds study

Scientists have developed the most accurate model yet of how the coronavirus particles rotate, according to their ellipsoidal shape.

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High folic acid supplementation associated with higher rates of COVID-19 infections and mortality, study finds

A new study that looked at health data from the UK found people with a folic acid prescription were 1.5 times as likely to get COVID-19 and were more than 2.6 times as likely to die from COVID-19 compared to the control group.

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How the brain processes sensory information from internal organs

Most of us think little of why we feel pleasantly full after eating a big holiday meal, why we start to cough after accidentally inhaling campfire smoke, or why we are hit with sudden nausea after ingesting something toxic. However, such sensations are crucial for survival: they tell us what our bodies need at any given moment so that we can quickly adjust our behavior.

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Sex differences and AFib: New study flips conventional wisdom

New research has found women -- when height is accounted for -- have a 50% higher risk of developing the abnormal heart rhythm disturbance when compared to men.

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New way found to turn number seven plastic into valuable products

A method to convert a commonly thrown-away plastic to a resin used in 3D-printing could allow for making better use of plastic waste.

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Positive neighbor involvement important if teens don't develop mother-child bond

Teens who live in neighborhoods with trusted, engaged adults can still develop critical social skills that were not nurtured early in life, according to a new study.

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Tuesday, August 30, 2022

Low-cost disease diagnosis by mapping heart sounds

Researchers develop a method to identify aortic valve dysfunction using complex network analysis that is accurate, simple to use, and low-cost. They used heart sound data to create a complex network of connected points, which was split into sections, and each part was represented with a node. If the sound in two portions was similar, a line was drawn between them. In a healthy heart, the graph showed two distinct clusters of points, with many nodes unconnected. A heart with aortic stenosis contained many more correlations and edges.

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Brain's support cells may hold key to new Huntington's treatments

A growing body of research suggests that the disease may also flow from defects in glia, important support cells found in the brain. The new study expands our understanding of the underlying mechanisms of the disease, and reinforces the potential of therapies that target glia cells.

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Possible new cancer treatment target discovered

Researchers have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice. This discovery may potentially enable future development of new drugs against a range of cancer diseases.

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New therapeutic prospect for preeclampsia

Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother. Scientists have proposed a new therapy, tested in two rodent models, that corrects the defects identified in placental cells, and restores placental and fetal weight. The treatment successfully lowers blood pressure in the mother and resolves the characteristic preeclampsia symptoms of excess protein in urine and cardiovascular abnormalities.

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Team developing oral insulin tablet sees breakthrough results

Researchers working on developing oral insulin tablets as a replacement for daily insulin injections have made a game-changing discovery. The researchers have discovered that insulin from the latest version of their oral tablets is absorbed by rats in the same way that injected insulin is.

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Monday, August 29, 2022

How the brain's housekeeper malfunctions during bacterial meningitis

Bacterial meningitis is a life-threatening infectious disease of the brain that leaves many survivors with long-lasting neurological impairments. Now, researchers show in a study on rats that the brain's tool for waste clearance, the glymphatic system, malfunctions during bacterial meningitis, causing a buildup of toxic garbage that damages brain cells.

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Microscopy technique reveals hidden nanostructures in cells and tissues

Researchers developed a way to 'de-crowd' molecules in a cell by expanding a tissue sample, labeling the molecules, then imaging them. The method, known as expansion revealing, builds on a technique known as expansion microscopy and should allow scientists to visualize molecules and cellular structures that have never been seen before.

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Brief exposure to rapamycin has the same anti-aging effects as lifelong treatment

Brief exposure with rapamycin has the same positive effects on lifespan and health in old age as a lifelong treatment, researchers show in fruit flies and mice. Rapamycin is currently the most promising anti-aging drug. To maximize the medicine's effectiveness, it is often administered for life. However, even at low doses used to prevent age-related decline, side effects can occur. Therefore, the shorter duration of treatment may make it more likely to be used in humans.

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White, red, and blue signals alert you to dangerous germs

Scientists developed a simple, rapid method for identifying food poisoning-inducing bacteria based on color differences in the scattered light of composite structures consisting of gold, silver, and copper nanoparticles and polymer particles. Using these composites as test labels bound to specific bacteria, the researchers detected food poisoning bacteria E. coli O26, E. coli O157, and S. aureus as white, red, and blue scattered light, respectively, under the microscope. This new method enables simultaneous identification of multiple bacterial species within one hour, significantly shortening the usual 48-hour time requirement for conventional bacterial tests.

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Boosting duration, intensity & frequency of physical activity may lower heart failure risk

Researchers tracked the incidence of heart failure over six years in more than 94,000 middle-aged adults in the U.K. Biobank who wore wrist accelerometers to record the amount and intensity of their physical activity over seven days between 2013-2015. Participants who engaged in 150-300 minutes of moderate physical activity or 75-150 minutes of vigorous physical activity during the week of observation reduced their risk of being hospitalized for or death from heart failure by two-thirds compared to participants who did not engage in the same amounts of moderate or vigorous physical activity during the week.

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Autoimmune disorders increase risk of cardiovascular disease

An international research team presents the outcome of a thorough epidemiological investigation into possible links between nineteen of the most common autoimmune disorders and cardiovascular disease. The results of the study show that patients with autoimmune disease have a substantially higher risk (between 1.4 and 3.6 times depending on which autoimmune condition) of developing cardiovascular disease than people without an autoimmune disorder.

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Half of moms of kids with autism have high depressive symptoms

About 50% of all mothers of children with autism spectrum disorder (ASD) had elevated levels of depressive symptoms over 18 months, while rates were much lower (6% to 13.6%) for mothers with neurotypical children in the same period, researchers report.

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Half of moms of kids with autism have high depressive symptoms

About 50% of all mothers of children with autism spectrum disorder (ASD) had elevated levels of depressive symptoms over 18 months, while rates were much lower (6% to 13.6%) for mothers with neurotypical children in the same period, researchers report.

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Keeping Kermit: New clues to protecting frogs from deadly Bd fungus

A new study shows that while Bd can significantly reduce in captive frogs, captivity can have negative consequences for the frogs' protective skin microbiota, providing new insight into diversity management.

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Cannabis legalization boosts use by double digits

A new first-of-its-kind study of twins finds that residents of states where recreational marijuana is legal use it 24% more frequently than those in states where it's illegal. It's among the strongest evidence yet that legalization increases use.

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How maternal fat metabolism very early in pregnancy and fetal abdominal growth influence toddler weight

A new study identifies, as early as the 5th month of pregnancy, patterns of fetal abdominal growth associated with maternal lipid metabolites that track newborn growth, adiposity and development into childhood. These fetal growth patterns are also associated with blood flow and nutrient transfer by the placenta, demonstrating a complex interaction between maternal and fetal nutrition early in pregnancy that influences postnatal weight and eventually adult health.

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Cannabis legalization boosts use by double digits

A new first-of-its-kind study of twins finds that residents of states where recreational marijuana is legal use it 24% more frequently than those in states where it's illegal. It's among the strongest evidence yet that legalization increases use.

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Friday, August 26, 2022

Majority of clinicians in U.S. safety net practices report 'moral distress' during COVID-19 pandemic, study finds

A recent study found that most healthcare providers experienced either mild or intense levels of moral distress during the first year of the pandemic due to issues related to patient care and their workplaces.

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Good sleepers have lower risk of heart disease and stroke

Nine in ten people do not get a good night's sleep, according to new research. The study found that suboptimal sleep was associated with a higher likelihood of heart disease and stroke. The authors estimated that seven in ten of these cardiovascular conditions could be prevented if everyone was a good sleeper.

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Potential threat to heart health from extreme weather

An analysis in nearly 2.3 million Europeans has found detrimental associations between cold weather and deaths from heart disease, particularly in poor neighbourhoods. Hot weather was linked with excess deaths from heart disease and stroke in patients with heart conditions.

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New treatment principle for chronic hepatitis B and D infections

A new immunological treatment against hepatitis B and D viruses, both of which can cause liver cancer, shows promising results in animal models.

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Illicit drugs are used by one in ten intensive cardiac care unit patients

Illicit drug use is associated with a nearly nine-fold greater risk of death or life-threatening emergencies in intensive cardiac care unit (ICCU) patients, according to new research.

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Thursday, August 25, 2022

Innate immunity: The final touch for antimicrobial defense

Immunologists have identified an important intermediate step in innate immune defense.

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Researchers design highly sensitive, mass producible organic photodetectors

Most of today's imaging sensors are based on CMOS technology and inorganic photodetectors that convert light signals into electric signals. Although photodetectors made from organic materials are attracting attention because they can help boost sensitivity, for example, it has proven difficult to fabricate high-performance organic photodetectors. Researchers now describe new green-light absorbing transparent organic photodetectors that are highly sensitive and compatible with CMOS fabrication methods. Incorporating these new photodetectors into organic-silicon hybrid image sensors could be useful for applications such as light-based heart-rate monitoring, fingerprint recognition and devices that detect the presence of nearby objects.

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Innate immunity: The final touch for antimicrobial defense

Immunologists have identified an important intermediate step in innate immune defense.

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'Synthetic' embryo with brain and beating heart grown from multiple stem cells

Researchers have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body -- a new avenue for recreating the first stages of life.

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Teachers want support to embrace nature play in primary education

While nature play infrastructure grows, new research from Australia shows that teachers also need a knowledge-boost on how to best link nature play areas to the curriculum and children's learning.

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'Synthetic' embryo with brain and beating heart grown from multiple stem cells

Researchers have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body -- a new avenue for recreating the first stages of life.

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Wednesday, August 24, 2022

Using digital media to relax is related to lower-quality parenting

Caregivers who consume digital media for relaxation are more likely to engage in negative parenting practices, according to a new multinational study.

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Large regional differences in agricultural adaptation to future climate change in Europe

Marked differences in how climate change will affect different parts of Europe require further focus and political attention if European agriculture is to adapt to future climatic conditions, say researchers.

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Reasons behind gamer rage in children are complex -- and children are good at naming them

Children's outbursts of rage while playing digital games are causing both concern and public debate around the topic. Taking a novel approach to gamer rage, a new study examines the topic from a child's perspective, finding complex reasons for gamer rage in children.

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Tracking the journey of mangroves in southern Japan

By using techniques from both genetics and oceanography, researchers have found that the mangrove populations in the Ryukyu Islands are relatively isolated from one another, which has implications for conservation.

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Reasons behind gamer rage in children are complex -- and children are good at naming them

Children's outbursts of rage while playing digital games are causing both concern and public debate around the topic. Taking a novel approach to gamer rage, a new study examines the topic from a child's perspective, finding complex reasons for gamer rage in children.

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Tuesday, August 23, 2022

Air pollution is associated with heart attacks in non-smokers

Research supports a causal relationship between air pollution and heart attacks since smokers, who already inhale smoke, were unaffected by dirty air.

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Boxing clever: Simple conservation strategy saving threatened Roseate terns

A simple conservation strategy deployed by conservationists and scientists is greatly assisting in the extraordinary success of threatened Roseate terns on Rockabill Island, off the coast of Dublin. Ireland is home to the majority of Europe's Roseate Terns with Rockabill incredibly hosting 85% of the European population on this tiny island, which is the size of a football pitch. The number of breeding pairs is now ten times what it was when the project started in 1989, and chicks that hatched and fledged on Rockabill have gone on to boost other important colonies in Wexford and England.

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Surprising culprit worsens stroke, TBI damage

A new study provides for the first time the surprising evidence that four common nonexcitatory amino acids that usually make proteins which are essential to brain function, instead cause irreversible, destructive swelling of both the astrocytes that support neurons and the neurons themselves in the aftermath of stroke, TBI.

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Surprising culprit worsens stroke, TBI damage

A new study provides for the first time the surprising evidence that four common nonexcitatory amino acids that usually make proteins which are essential to brain function, instead cause irreversible, destructive swelling of both the astrocytes that support neurons and the neurons themselves in the aftermath of stroke, TBI.

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People who use therapeutic cannabis are more likely to use nicotine, too

People who use therapeutic cannabis are more likely to also use nicotine products than the general population, according to a new study.

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People who use therapeutic cannabis are more likely to use nicotine, too

People who use therapeutic cannabis are more likely to also use nicotine products than the general population, according to a new study.

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Monday, August 22, 2022

Brains cells born together wire and fire together for life

Brain cells with the same 'birthdate' are more likely to wire together into cooperative signaling circuits that carry out many functions, including the storage of memories, a new study finds.

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Dogs cry more when reunited with their owners

Dogs and humans clearly have a special bond. But do dogs, like humans, produce more tears at times when they are flooded with emotion? A new study says that, indeed, the eyes of our canine companions do well up with tears. In fact, it happens regularly when they're reunited with you.

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What fake news about spiders can teach us about the global spread of (mis)information

It's no secret that the internet and social media fuel rampant spread of (mis)information in many areas of life. Now, researchers have explored this phenomenon as it applies to news about spiders. The verdict? Don't blindly trust anything you read online about these eight-legged arthropods -- or anything else for that matter -- and always consider the source.

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Sulfur shortage: A potential resource crisis looming as the world decarbonizes

A new study highlights that global demand for sulfuric acid is set to rise significantly from '246 to 400 million tons' by 2040 -- a result of more intensive agriculture and the world moving away from fossil fuels. A projected shortage of sulfuric acid, a crucial chemical in our modern industrial society, could stifle green technology advancement and threaten global food security, according to a new study.

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How recovery progresses following inflammation triggered by injury or illness

New findings reveal how recovery progresses following inflammation triggered by injury or illness.

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How recovery progresses following inflammation triggered by injury or illness

New findings reveal how recovery progresses following inflammation triggered by injury or illness.

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Friday, August 19, 2022

Robotic kidney cancer surgery shows desirable outcomes in study

Robotic surgery compared favorably with standard surgery in a review and analysis of data from 1,375 patients who underwent surgery to remove cancer from the kidney and inferior vena cava. The inferior vena cava (IVC), the body's biggest vein, carries blood out of the kidneys back to the heart. Cancer can infiltrate this vein and advance to the liver and heart. Robotic IVC thrombectomy resulted in fewer blood transfusions and fewer complications overall in patients compared to standard, open IVC thrombectomy. The findings should compel further studies of the benefits of robotic IVC thrombectomy.

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How do you take a better image of atom clouds? Mirrors -- lots of mirrors

To capture as much information as possible about clouds of atoms at the heart of the MAGIS-100 experiment, scientists devised a dome of mirrors that gathers more light from more angles.

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How nurses learn to assess pain levels in infants

Adults self-report their pain on a one to 10 numerical score, while children can point to an equivalent face scale -- from a green smiling face to a red crying face -- to indicate their pain. Newborns, however, cannot say a number or point to a face, leaving it up to their caregivers to identify and evaluate any pain they may be in. Until the turn of this century, a significant number of clinicians did not recognize that neonates could even experience pain, resulting in infrequent, nonstandard training for medical workers. Now, researchers are reporting that a flexible e-learning program improves neonate pain management knowledge and skills for nurses.

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Compost to computer: Bio-based materials used to salvage rare earth elements

What do corncobs and tomato peels have to do with electronics? They both can be used to salvage valuable rare earth elements, like neodymium, from electronic waste. Researchers used micro- and nanoparticles created from the organic materials to capture rare earth elements from aqueous solutions.

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Robotic kidney cancer surgery shows desirable outcomes in study

Robotic surgery compared favorably with standard surgery in a review and analysis of data from 1,375 patients who underwent surgery to remove cancer from the kidney and inferior vena cava. The inferior vena cava (IVC), the body's biggest vein, carries blood out of the kidneys back to the heart. Cancer can infiltrate this vein and advance to the liver and heart. Robotic IVC thrombectomy resulted in fewer blood transfusions and fewer complications overall in patients compared to standard, open IVC thrombectomy. The findings should compel further studies of the benefits of robotic IVC thrombectomy.

from Top Health News -- ScienceDaily https://ift.tt/4T9FfKp

How nurses learn to assess pain levels in infants

Adults self-report their pain on a one to 10 numerical score, while children can point to an equivalent face scale -- from a green smiling face to a red crying face -- to indicate their pain. Newborns, however, cannot say a number or point to a face, leaving it up to their caregivers to identify and evaluate any pain they may be in. Until the turn of this century, a significant number of clinicians did not recognize that neonates could even experience pain, resulting in infrequent, nonstandard training for medical workers. Now, researchers are reporting that a flexible e-learning program improves neonate pain management knowledge and skills for nurses.

from Top Health News -- ScienceDaily https://ift.tt/fw9TX8p

Immune cell model paves way for new treatments targeting common infection amongst immunocompromised children

Researchers have successfully engineered human immune cells to model an infection common among immunocompromised people in a breakthrough discovery, paving the way for new drug testing and treatments.

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New method enables long-lasting imaging of rapid brain activity in individual cells deep in the cortex

A new sensor that allows neuroscientists to image brain activity without missing signals, for an extended time and deeper in the brain than previously possible.

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Thursday, August 18, 2022

New SPARK study identifies a novel group of inherited genes of moderate effect and shows their links to other behavioral conditions

Researchers used data from the SPARK (Simons Powering Autism Research) research cohort, which was created to advance our understanding of the complex genetics of autism and includes genetic data from nearly 43,000 people with autism. The findings show differences in genetic influences among people all along the autism spectrum.

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Breaking in a new planet

Impacts affect the porosity and structure of moons and planets more dramatically than scientists suspected, increasing their potential habitability for life. Studying how those impacts affect planetary bodies, asteroids, moons and other rocks in space helps planetary scientists understand extraplanetary geology, especially where to look for precious matter including water, ice and even, potentially, microbial life.

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Researchers design new inks for 3D-printable wearable bioelectronics

A team of researchers has developed a new class of biomaterial inks that mimic native characteristics of highly conductive human tissue, much like skin, which are essential for the ink to be used in 3D printing.

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Museum collections indicate bees increasingly stressed by changes in climate over the past 100 years

An analysis of bumblebee wings from a network of UK museums shows signs of stress linked to increasingly hotter and wetter conditions.

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Report outlines most common symptoms of 6 cardiovascular diseases

A 'state of the science' review details the most reported symptoms of 6 cardiovascular diseases (CVDs): heart attack, heart failure, valve disease, stroke, heart rhythm disorders, and peripheral artery and vein disease (PAD and PVD). There are important differences in symptoms between women and men. Depression, common across many CVDs, may influence a person's ability to detect changes in symptoms. Effective methods of monitoring and measuring symptoms over time are critical to manage cardiovascular disease well and prevent or delay its progression.

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Wednesday, August 17, 2022

Online teaching triggers a different response in the body

Numerous studies have shown that people relate to online teaching in a different way than to in-person classes. Now researchers have explored whether the body also experiences a difference.

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Interdisciplinary panel offers solutions to improve recruitment for Alzheimer's clinical trials

Researchers aim to develop solutions to overcome some of the steepest barriers to clinical trial recruitment.

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How hepatitis E tricks the immune system

Over three million people are infected with the hepatitis E virus every year. So far, no effective treatment is available. An international team has investigated which factors are important for the virus in the course of its replication cycle and how it manages to maintain the infection. The researchers analysed various mutations of the virus and found changes that may allow the virus to trick the immune system.

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Smartphone video motion analysis detected narrowed neck arteries that may lead to stroke

In a small study, motion analysis of video recorded on a smartphone accurately identified narrowed neck arteries in adults, which are a risk factor for stroke. The smartphone video motion analysis technology may be an early screening tool for detecting narrowed arteries in the neck, which may improve patient outcomes.

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Smartphone video motion analysis detected narrowed neck arteries that may lead to stroke

In a small study, motion analysis of video recorded on a smartphone accurately identified narrowed neck arteries in adults, which are a risk factor for stroke. The smartphone video motion analysis technology may be an early screening tool for detecting narrowed arteries in the neck, which may improve patient outcomes.

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Tuesday, August 16, 2022

Delays in contact tracing impeded early COVID-19 containment

Contact tracing programs were deployed around the globe to slow the spread of COVID-19, but these programs could not prevent the multiple waves of transmission and loss of life that have occurred since March 2020. Researchers found that a five-day delay between identifying a case and isolating contacts was the Achilles' heel of a contact tracing program in a large U.S. city.

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Low school test scores linked to racial segregation and lead exposure in North Carolina

Birth data, blood lead levels and fourth grade end-of-grade test scores for more than 25,000 children living in North Carolina show how childhood lead exposure and neighborhood racial residential segregation affect early childhood educational outcomes. Identifying the mix of social, environmental and economic factors that create health disparities early could lead to earlier intervention in vulnerable communities, thus narrowing the 'achievement gap' that becomes apparent in early childhood and persists or widens with time.

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Low school test scores linked to racial segregation and lead exposure in North Carolina

Birth data, blood lead levels and fourth grade end-of-grade test scores for more than 25,000 children living in North Carolina show how childhood lead exposure and neighborhood racial residential segregation affect early childhood educational outcomes. Identifying the mix of social, environmental and economic factors that create health disparities early could lead to earlier intervention in vulnerable communities, thus narrowing the 'achievement gap' that becomes apparent in early childhood and persists or widens with time.

from Latest Science News -- ScienceDaily https://ift.tt/Ytl4RUk

Scientists uncover a new role for blood-brain barrier in neuron function and damage

Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endothelial layer in the vertebrate blood-brain barrier, form the key cellular layer that is critical for axonal ensheathment and the blood-brain barrier in Drosophila. The results provide a mechanistic insight into the biology of barrier function and glia-neuron interactions.

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Chagas: Less neglect for a neglected tropical disease

A research group implemented a survey over two years to assess vector infestation and the infection risk of the parasite Trypanosoma cruzi in triatomine bugs, the culprits responsible for Chagas disease, throughout El Salvador. Their findings showed the nationwide ubiquity of the principal insect vector and identified areas where these insects have high Trypanosoma cruzi infection rates. The results contribute to potential cost-effective vector control efforts that concentrate attention and resource allocation to highly infected areas in El Salvador.

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Scientists uncover a new role for blood-brain barrier in neuron function and damage

Researchers have made a surprising discovery linking Delta/Notch signaling in subperineurial glia (SPG) to the regulation of nerve ensheathment and neurotransmitter release at the Drosophila neuromuscular junction (NMJ). SPG, the counterpart of the endothelial layer in the vertebrate blood-brain barrier, form the key cellular layer that is critical for axonal ensheathment and the blood-brain barrier in Drosophila. The results provide a mechanistic insight into the biology of barrier function and glia-neuron interactions.

from Latest Science News -- ScienceDaily https://ift.tt/4ZPg79c

Monday, August 15, 2022

Rhodiola rosea root might be beneficial for managing type 2 diabetes

A team of researchers has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

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National parks -- islands in a desert?

How effective is biodiversity conservation of European and African national parks? This seems to be strongly associated with societal and economic conditions. But even under the most favorable conditions, conservation efforts cannot completely halt emerging threats to biodiversity if conditions outside of the parks do not improve.

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Rhodiola rosea root might be beneficial for managing type 2 diabetes

A team of researchers has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

from Top Health News -- ScienceDaily https://ift.tt/SlAPXr9

Colorful solar panels could make the technology more attractive

Solar panels aren't just for rooftops anymore -- some buildings even have these power-generating structures all over their facades. But as more buildings and public spaces incorporate photovoltaic technologies, their monotonous black color could leave onlookers underwhelmed. Now, researchers have created solar panels that take on colorful hues while producing energy nearly as efficiently as traditional ones.

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Hormone from fat cells restrains tumor growth in mice

A hormone secreted by fat cells can restrain the growth of liver tumors in mice, according to a new study.

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Hormone from fat cells restrains tumor growth in mice

A hormone secreted by fat cells can restrain the growth of liver tumors in mice, according to a new study.

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Sunday, August 14, 2022

Minorities bore disproportionate mental health impact of pandemic

Racial and ethnic minorities bore a disproportionate mental health burden during the COVID-19 pandemic, according to a new study.

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Declines in opioid prescriptions for U.S. patients with cancer and non-cancer pain, study shows

The number of privately insured adults in the United States prescribed opioid medications for cancer pain and for chronic non-cancer pain declined between 2012 and 2019, according to a new study.

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Saturday, August 13, 2022

Will strong and fast-switching artificial muscle be feasible?

A research team has developed a bifunctional polymer electrolyte with enhanced mechanical strength and ionic conductivity. The new technology can be applied to producing strong artificial muscles with fast switching speeds.

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Using sound and bubbles to make bandages stickier and longer lasting

Researchers have discovered that they can control the stickiness of adhesive bandages using ultrasound waves and bubbles. This breakthrough could lead to new advances in medical adhesives, especially in cases where adhesives are difficult to apply such as on wet skin.

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Vegetarian women are at a higher risk of hip fracture

A study of over 26,000 middle-aged UK women reveals those with a vegetarian diet had a 33% higher risk of hip fracture compared to regular meat-eaters.

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Vegetarian women are at a higher risk of hip fracture

A study of over 26,000 middle-aged UK women reveals those with a vegetarian diet had a 33% higher risk of hip fracture compared to regular meat-eaters.

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More than meets the eye: How patterns in nature arise and inspire everything from scientific theory to biodegradable materials

New research sheds light on how a certain kind of pattern in nature arises.

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Friday, August 12, 2022

PET scan visualization can measure effects of STING-activating drugs

A new study suggests that readily available PET scanning could enable a whole-body analysis of the effects of systemic STING-activating therapy in humans, potentially providing a diagnostic tool to guide clinical development of this treatment approach.

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New study reveals computation-guided approach to suppressing cancer tumor growth

A new study reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers. This approach was successful both in vitro and in vivo. This strategy can increase chemical diversity of p53 corrector molecules for clinical development.

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New research reveals the circadian clock influences cell growth, metabolism and tumor progression

In a new study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression. Their research also reveals how disruption of the circadian clock impacts genome stability and mutations that can further drive critical tumor promoting pathways in the intestine.

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AI may come to the rescue of future firefighters

In firefighting, the worst flames are the ones you don't see coming. Amid the chaos of a burning building, it is difficult to notice the signs of impending flashover -- a deadly fire phenomenon wherein nearly all combustible items in a room ignite suddenly. Flashover is one of the leading causes of firefighter deaths, but new research suggests that artificial intelligence (AI) could provide first responders with a much-needed heads-up.

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Multiple sclerosis drug works in a surprising way

Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce proinflammatory molecules and even increase production of anti-inflammatory species in MS patients. But researchers now report that the molecule reduces the binding of three components -- zinc, C-peptide and albumin -- to red blood cells.

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Thursday, August 11, 2022

Brain scans reveal the hidden shape of thinking and predict students' learning better than test scores

Neuroscientists have documented a link between spatial and verbal reasoning by scanning students' brains while taking a course that emphasized spatial learning.

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Study finds that sound plus electrical body stimulation has potential to treat chronic pain

A team has found that electrical stimulation of the body combined with sound activates the brain's somatosensory cortex, increasing the potential for using the technique to treat chronic pain and other sensory disorders.

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Building on the moon and Mars? You'll need extraterrestrial cement for that

Researchers are exploring ways to use clay-like topsoil materials from the moon or Mars as the basis for extraterrestrial cement that could be used by astronauts to create building materials for life in outer space. Scientists have converted simulated lunar and Martian soils into geopolymer cement, which is considered a good substitute for conventional cement.

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Brain scans reveal the hidden shape of thinking and predict students' learning better than test scores

Neuroscientists have documented a link between spatial and verbal reasoning by scanning students' brains while taking a course that emphasized spatial learning.

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Sponges 'sneeze' to dispose of waste

Sneezing out mucus may be one of the oldest ways for organisms to get rid of unwanted waste. A group of researchers found that sponges, one of the oldest multicellular organisms in existence, 'sneeze' to unclog their internal filter systems that they use to capture nutrients from the water. Additionally, authors find that other animals who live with the sponges use their mucus as food.

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Wednesday, August 10, 2022

Modeling moving 'washers' that help DNA replicate

Researchers have modeled a key mechanism by which DNA replicates. The study could help identify new targets to treat disease.

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Targeting impulsivity early in adolescence could prevent later behavioral disorders

A new study following hundreds of youth over more than a half-dozen years suggests that targeting adolescents who exhibit high levels of impulsivity in early adolescence could halt a cascading chain of events that leads to late-adolescence antisocial personality disorder and alcohol use disorder.

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Targeting impulsivity early in adolescence could prevent later behavioral disorders

A new study following hundreds of youth over more than a half-dozen years suggests that targeting adolescents who exhibit high levels of impulsivity in early adolescence could halt a cascading chain of events that leads to late-adolescence antisocial personality disorder and alcohol use disorder.

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Evidence that giant meteorite impacts created the continents

New research has provided the strongest evidence yet that Earth's continents were formed by giant meteorite impacts that were particularly prevalent during the first billion years or so of our planet's four-and-a-half-billion year history.

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Even modest climate change may lead to sweeping changes in northernmost forests

Even relatively modest climate warming and associated precipitation shifts may dramatically alter Earth's northernmost forests, which constitute one of the planet's largest nearly intact forested ecosystems and are home to a big chunk of the planet's terrestrial carbon.

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Ultracold atoms dressed by light simulate gauge theories

Researchers have used the coldest systems in the universe to realize in the laboratory gauge theories, key models of modern physics that describe the fundamental forces of Nature and the behavior of complex quantum materials.

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Climate change leads to invasive insect expansion on West Coast

Climate change has led to warming temperatures in the Pacific Northwest, leading some insect species to expand their range into more northerly oak savannas, according to new research.

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Tuesday, August 9, 2022

Clearing the mist hiding the genome

A team has developed a new mathematical method that can eliminate signal noise and thus enable the extraction of clear signals from single-cell RNA sequencing data. The new method successfully decreases random sampling noise in the data to enable a precise and complete understanding of a cell's activity.

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AI pilot can navigate crowded airspace

Researchers have developed an AI pilot that enables autonomous aircraft to navigate a crowded airspace. The artificial intelligence can safely avoid collisions, predict the intent of other aircraft, track aircraft and coordinate with their actions, and communicate over the radio with pilots and air traffic controllers. The researchers aim to develop the AI so the behaviors of their system will be indistinguishable from those of a human pilot.

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Circadian clocks play a key role in fat cell growth

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies.

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New target for therapies to treat preterm labor

Researchers have identified a cause of preterm labor, an enigma that has long challenged researchers. New research suggests a protein, called Piezo1, is responsible for regulating the behavior of the uterus. Piezo1 keeps the uterus relaxed ensuring that it continues to stretch and expand during the 40 weeks it takes a fetus to grow.

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Symptoms of insomnia may reduce likelihood of alcohol-induced blackout

Heavy drinkers with symptoms of insomnia, such as difficulty falling or staying asleep, may be less likely to suffer alcohol-induced blackouts, according to a new study.

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More wolves, beavers needed as part of improving western United States habitats

Scientists are proposing management changes on western federal lands that they say would result in more wolves and beavers and would re-establish ecological processes.

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Monday, August 8, 2022

Into the brain of comb jellies: Scientists explore the evolution of neurons

A new study into the neurons found in the earliest-diverging animal lineages reveals key clues about the form of the most ancestral nervous system, and how neurons first evolved.

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Impact of climate change on human pathogenic diseases subject of new study by UH researchers

A comprehensive assessment of scientific literature has uncovered empirical evidence that more than 58% of human diseases caused by pathogens, such as dengue, hepatitis, pneumonia, malaria, Zika and more, have been--at some point--aggravated by climatic hazards.

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Robotic motion in curved space defies standard laws of physics

Researchers have proven that when bodies exist in curved spaces, they can in fact move without pushing against something.

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New wind sensor uses smart materials to improve drone performance

Engineers have designed and successfully tested a more efficient wind sensor for use on drones, balloons and other autonomous aircraft.

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Scientists create long-acting injectable drug delivery system for tuberculosis

Research in animal models showed the potential of delivering a TB drug with one injection that lasts at least four months, in lieu of the current standard treatment requiring constant adherence to a daily drug regimen.

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Risk of death rises as climate change causes nighttime temperatures to climb

Excessively hot nights caused by climate change are predicted to increase the mortality rate around the world by up to 60% by the end of the century, according to a new international study.

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Cystic fibrosis: Causal treatment suitable from childhood

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy. A new combination drug therapy which addresses the disorder's underlying defects offers a promising new treatment approach. The use of this therapy had previously been limited to adolescents and adults. Designed to meet the highest standards of clinical practice, a study has now confirmed that this combination therapy regimen is also beneficial to primary school-aged children. Earlier treatment means disease progression is likely to be significantly slowed.

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Deciphering a baby's cries of pain is not an innate ability and must be learned

Before young children learn to speak, crying is their only means of vocal communication. But do adults know when a baby is in pain as opposed to being mildly uncomfortable? A new study finds that the answer to this question is that it depends.

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Sunday, August 7, 2022

Growing cereal crops with less fertilizer

Researchers have found a way to reduce the amount of nitrogen fertilizer needed to grow cereals such as rice, wheat and corn.

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'Simple yet powerful': Seeing cell secretion like never before

A research team has developed an assay that is versatile, low-cost and adaptable to any laboratory setting and has the potential to provide a more comprehensive look at proteins secreted by cells than the widely used existing assays.

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Researchers gain insights into the genetic and molecular machinery that predisposes individuals to Alzheimer's disease

Researchers have achieved an unprecedented understanding of the genetic and molecular machinery in human microglia -- immune cells that reside in the brain -- that could provide valuable insights into how they contribute to the development and progression of Alzheimer's disease (AD).

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Locusts can 'sniff' out human cancer

Researchers have shown that locusts can not only 'smell' the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

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New study explores cell receptor crucial for cardiovascular health

Cardiovascular diseases remain a leading cause of death around the world. A primary contributor to these afflictions is high blood pressure, or hypertension. While treatments exist for the condition, which affects tens of millions of Americans, these remedies are not without side effects, and some variants of the disorder are treatment-resistant. The need for more effective therapies to address hypertension-related disease is therefore acute. To accomplish this however, biologists need more detailed maps of the mechanisms underlying cardiovascular regulation. One such regulator is a protein receptor that sits atop cardiovascular cells, acting as a conduit for messages that are transmitted when specific hormone molecules bind with them.

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Locusts can 'sniff' out human cancer

Researchers have shown that locusts can not only 'smell' the difference between cancer cells and healthy cells, but they can also distinguish between different cancer cell lines.

from Latest Science News -- ScienceDaily https://ift.tt/6758vHp

New study explores cell receptor crucial for cardiovascular health

Cardiovascular diseases remain a leading cause of death around the world. A primary contributor to these afflictions is high blood pressure, or hypertension. While treatments exist for the condition, which affects tens of millions of Americans, these remedies are not without side effects, and some variants of the disorder are treatment-resistant. The need for more effective therapies to address hypertension-related disease is therefore acute. To accomplish this however, biologists need more detailed maps of the mechanisms underlying cardiovascular regulation. One such regulator is a protein receptor that sits atop cardiovascular cells, acting as a conduit for messages that are transmitted when specific hormone molecules bind with them.

from Latest Science News -- ScienceDaily https://ift.tt/ilUNhkm

Saturday, August 6, 2022

New recommendations aim to ease patient access to lung cancer clinical trials

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

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The many ways nature nurtures human well-being

A systematic review of 301 academic articles on 'cultural ecosystem services' has enabled researchers to identify how these nonmaterial contributions from nature are linked to and significantly affect human well-being. They identified 227 unique pathways through which human interaction with nature positively or negatively affects well-being. These were then used to isolate 16 distinct underlying mechanisms, or types of connection, through which people experience these effects. This comprehensive review brings together observations from a fragmented field of research, which could be of great use to policymakers looking to benefit society through the careful use and protection of the intangible benefits of nature.

from Top Health News -- ScienceDaily https://ift.tt/onxEkq6

The many ways nature nurtures human well-being

A systematic review of 301 academic articles on 'cultural ecosystem services' has enabled researchers to identify how these nonmaterial contributions from nature are linked to and significantly affect human well-being. They identified 227 unique pathways through which human interaction with nature positively or negatively affects well-being. These were then used to isolate 16 distinct underlying mechanisms, or types of connection, through which people experience these effects. This comprehensive review brings together observations from a fragmented field of research, which could be of great use to policymakers looking to benefit society through the careful use and protection of the intangible benefits of nature.

from Latest Science News -- ScienceDaily https://ift.tt/onxEkq6

Friday, August 5, 2022

Nutrition solution can help heat-stressed cows as US warms

Rising temperatures pose major challenges to the dairy industry -- a Holstein's milk production can decline 30 to 70% in warm weather -- but a new study has found a nutrition-based solution to restore milk production during heat-stress events, while also pinpointing the cause of the decline.

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When a task adds more steps, this circuit helps you notice

By tracking feedback during tasks, the anterior cingulate cortex notices when a new step has become necessary and signals the motor cortex to adjust, a new neuroscience study shows.

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When a task adds more steps, this circuit helps you notice

By tracking feedback during tasks, the anterior cingulate cortex notices when a new step has become necessary and signals the motor cortex to adjust, a new neuroscience study shows.

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Thursday, August 4, 2022

Sterile mice produce rat sperm

Researchers generated rat sperm cells inside sterile mice using a technique called blastocyst complementation.

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A new therapeutic drug for Alzheimer's disease without inflammatory side effects

Although Aduhelm, a monoclonal antibody targeting amyloid beta (A?), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease A? plaque burden in AD patients, its effect on cognitive improvement is still controversial. Moreover, about 40% of the patients treated with this antibody experienced serious side effects including cerebral edemas (ARIA-E) and hemorrhages (ARIA-H) that are likely related to inflammatory responses in the brain when the A? antibody binds Fc receptors (FCR) of immune cells such as microglia and macrophages. Now there is a new option.

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Speeding up evolution at genome-level by alternative chromosome configuration

A research team has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution.

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A new therapeutic drug for Alzheimer's disease without inflammatory side effects

Although Aduhelm, a monoclonal antibody targeting amyloid beta (A?), recently became the first US FDA approved drug for Alzheimer's disease (AD) based on its ability to decrease A? plaque burden in AD patients, its effect on cognitive improvement is still controversial. Moreover, about 40% of the patients treated with this antibody experienced serious side effects including cerebral edemas (ARIA-E) and hemorrhages (ARIA-H) that are likely related to inflammatory responses in the brain when the A? antibody binds Fc receptors (FCR) of immune cells such as microglia and macrophages. Now there is a new option.

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Potential target for treatment among patients with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers has identified a therapeutic target for the preservation and regeneration of beta cells -- cells in the pancreas that produce and distribute insulin.

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Potential target for treatment among patients with type 2 diabetes

In a potential game changer for patients with type 2 diabetes, a team of researchers has identified a therapeutic target for the preservation and regeneration of beta cells -- cells in the pancreas that produce and distribute insulin.

from Latest Science News -- ScienceDaily https://ift.tt/BPl0HXs

Wednesday, August 3, 2022

After breakups, people feel less in-control -- but only at first

A new analysis of people who underwent different types of relationship loss found that these experiences were linked with different patterns of short- and long-term sense of control following the loss.

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Perceived choice in music listening is linked to pain relief

A new study explores the use of music-listening to relieve acute pain, finding that people who were given the impression that they had control over the music they heard experienced more pain relief than people who were not given such control.

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Genes involved in heart disease are similar across all populations, study finds

The genes involved in coronary heart disease, the most common form of heart disease, appear to be nearly the same for everyone, according to a new study.

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Genes involved in heart disease are similar across all populations, study finds

The genes involved in coronary heart disease, the most common form of heart disease, appear to be nearly the same for everyone, according to a new study.

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Gesture-based communication techniques may ease video meeting challenges

Researchers have developed and demonstrated the potential benefit of a simple set of physical gestures that participants in online group video meetings can use to improve their meeting experience.

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After breakups, people feel less in-control -- but only at first

A new analysis of people who underwent different types of relationship loss found that these experiences were linked with different patterns of short- and long-term sense of control following the loss.

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New global map of ant biodiversity reveals areas that may hide undiscovered species

Researchers have combined data from around the world with predictions from machine learning to create a high-resolution map of ant diversity, revealing areas that should be the focus of exploration and research.

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Tuesday, August 2, 2022

New national guidelines aim to prevent obesity in midlife women

Women between 40 and 60 years old are the focus of new national guidelines aimed at preventing unhealthy weight gain that can lead to serious illness.

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Global forest area per capita has decreased by over 60 percent, study finds

Over the past 60 years, the global forest area has declined by 81.7 million hectares, a loss that contributed to the more than 60 percent decline in global forest area per capita. This loss threatens the future of biodiversity and impacts the lives of 1.6 billion people worldwide, according to a new study.

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Why breast-fed premature infants have a healthier gut than formula-fed ones

New research found it is not just the content of breastmilk that makes the difference. It is also the way the babies digest it.

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Why breast-fed premature infants have a healthier gut than formula-fed ones

New research found it is not just the content of breastmilk that makes the difference. It is also the way the babies digest it.

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Gene therapy approach shows promise in treating ALS

Researchers report that a gene therapy approach, developed measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families.

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Affordable and sustainable alternative to lithium-ion batteries proposed

Concerns regarding scarcity, high prices, and safety regarding the long-term use of lithium-ion batteries has prompted a team of researchers to propose a greener, more efficient, and less expensive energy storage alternative.

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Gene therapy approach shows promise in treating ALS

Researchers report that a gene therapy approach, developed measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families.

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Monday, August 1, 2022

New discovery of panda species which may have been Europe's last

Lumbering through the forested wetlands of Bulgaria around six million years ago, a new species of panda has been uncovered by scientists who state it is currently the last known and 'most evolved' European giant panda.

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A molecule of light and matter

A very special bonding state between atoms has been created in the laboratory: With a laser beam, atoms can be polarized so that they are positively charged on one side and negatively charged on the other. This makes them attract each other creating a very special bonding state -- much weaker than the bond between two atoms in an ordinary molecule, but still measurable. The attraction comes from the polarized atoms themselves, but it is the laser beam that gives them the ability to do so -- in a sense, it is a 'molecule' of light and matter.

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Sound of music: Ultrasound exposure improves depressive behavior in rodents

It is well known that whole-body exposure to high frequency ultrasound increases brain activity in humans. However, little is known about its impact and associated mechanisms on emotional states like depression. Now researchers have recently demonstrated the anti-depressant effects of ultrasound exposure in a rodent model of depression. Their findings shed light on the potential of ultrasound exposure as a non-invasive treatment for mental disorders.

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New method to promote biofilm formation and increase efficiency of biocatalysis

The researchers identified a library of synthetic polymers and screened them for their ability to induce biofilm formation in E. coli, a bacterium that is one of the most widely studied micro-organisms, and commonly used in biocatalysis.

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Insight into how congenital heart defects manifest

In an effort to learn more about how the heart develops, researchers have determined that the cells lining the heart direct the cardiac muscle to grow until the heart reaches its full size. They also outlined the complex mechanism that regulates this process, which requires two sets of brakes to be bypassed for the heart to develop properly.

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Life expectancy drops for Native Americans due to COVID-19

The pandemic reduced Native American life expectancy at birth from the already low 72 years in 2019 to about 67 years in 2020 and about 65 years in 2021 for both sexes combined.

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A stable gut helps elite athletes perform better

New research has found that microbial instability in the gut could hinder the performance of elite endurance athletes, and that short-term, high-protein diets are associated with this type of imbalance.

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Diets higher in calcium and potassium may help prevent recurrent symptomatic kidney stones

Kidney stones can cause not only excruciating pain but also are associated with chronic kidney disease, osteoporosis and cardiovascular disease. If you've experienced a kidney stone once, you have a 30% chance of having another kidney stone within five years.

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Children who lack sleep may experience detrimental impact on brain and cognitive development that persists over time

Elementary school-age children who get less than nine hours of sleep per night have significant differences in certain brain regions responsible for memory, intelligence and well-being compared to those who get the recommended nine to 12 hours of sleep per night, according to a new study.

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Space travel: Bone aging in fast forward

Long periods in space damage bone structure irreparably in some cases and can make parts of the human skeleton age prematurely by up to 10 years, according to new research. Adapted training programs in conjunction with medication could provide better protection for astronauts on future space missions. The research findings also have implications for treating rheumatic conditions in clinical practice.

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A stable gut helps elite athletes perform better

New research has found that microbial instability in the gut could hinder the performance of elite endurance athletes, and that short-term, high-protein diets are associated with this type of imbalance.

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Pinpointing consciousness in animal brain using mouse 'brain map'

Science may be one step closer to understanding where consciousness resides in the brain. A new study shows the importance of certain types of neural connections in identifying consciousness.

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Pinpointing consciousness in animal brain using mouse 'brain map'

Science may be one step closer to understanding where consciousness resides in the brain. A new study shows the importance of certain types of neural connections in identifying consciousness.

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Only 13 % know: The one-minute self-exam that could save young men’s lives

A new survey shows most Americans wrongly think testicular cancer is an older man's issue, despite it most commonly affecting men aged 2...