Monday, January 4, 2021

Drug discovery study identifies promising new compound to open constricted airways

In a preclinical study, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle cells. The cross-disciplinary team found 1,10 phenanthroline-5,6-dione (T5-8 for short) was 1,000 times more potent than some of the other bronchodilator agonists tested, and it demonstrated marked effectiveness in human airway smooth muscle cells grown in the laboratory.

from Latest Science News -- ScienceDaily https://ift.tt/3rPFww1
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Study finds untreated sleep apnea doubles Parkinson’s risk

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