Researchers light-up mouse brain, revealing previously hidden areas susceptible to opioids

New work shows that kappa opioid receptors actually are distributed widely throughout the brain. The researchers made this discovery after lighting up the brains of mice using a technique called CLARITY followed by three-dimensional (3D) fluorescent imaging. The study is the first to apply the imaging technique to better understand opioid receptor localization across the whole brain in 3D images.

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