Preclinical research shows a pivotal role for cellular metabolism to regulate the fate decision of naïve CD4 T cells as they differentiate into either destructive Th17 cells that mediate chronic inflammation or regulatory Treg T cells, a decision that occurs very early in the activation of CD4 T cells. This opens a possibility that manipulating the cellular metabolism of T cells may provide a therapeutic intervention in chronic autoimmune disorders.
from Latest Science News -- ScienceDaily https://ift.tt/2uB73bU
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