Wednesday, February 27, 2019

Reprogramming the wonder drug rapamycin allows creation of new small-molecule drugs

In the new study, the authors aimed to reprogram rapamycin by keeping the parts of rapamycin and tacrolimus that bind FKBP12 and changing the remaining half of the molecule in order to target completely new disease-associated proteins beyond mTOR and calcineurin.

from Latest Science News -- ScienceDaily https://ift.tt/2BZbUnD
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Scientists reverse liver cell aging and cut Alzheimer’s-linked protein in half

A surprising discovery suggests that rejuvenating the liver could help protect against Alzheimer’s disease and heart disease. USC researcher...