Study finds untreated sleep apnea doubles Parkinson’s risk

A massive veteran study found a strong connection between untreated sleep apnea and a higher chance of Parkinson’s. CPAP users had much lower odds of developing the condition. Researchers believe that repeated dips in oxygen during sleep may strain neurons over time. The results suggest that better sleep might help protect the brain.

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New study shows rheumatoid arthritis begins long before symptoms

Rheumatoid arthritis begins years before pain ever appears, and scientists have now mapped the hidden immune battle that unfolds long before symptoms. By studying people with RA-linked antibodies over seven years, researchers discovered sweeping inflammation, malfunctioning immune cells, and even epigenetic reprogramming in cells that had never encountered a threat. These changes show that the body is preparing for autoimmune attack long before joints become damaged.

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New study shows rheumatoid arthritis begins long before symptoms

Rheumatoid arthritis begins years before pain ever appears, and scientists have now mapped the hidden immune battle that unfolds long before symptoms. By studying people with RA-linked antibodies over seven years, researchers discovered sweeping inflammation, malfunctioning immune cells, and even epigenetic reprogramming in cells that had never encountered a threat. These changes show that the body is preparing for autoimmune attack long before joints become damaged.

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Scientists discover a hidden deep sea hotspot bursting with life

Beneath the waters off Papua New Guinea lies an extraordinary deep-sea environment where scorching hydrothermal vents and cool methane seeps coexist side by side — a pairing never before seen. This unusual chemistry fuels a vibrant oasis teeming with mussels, tube worms, shrimp, and even purple sea cucumbers, many of which may be unknown to science. The rocks themselves shimmer with traces of gold, silver, and other metals deposited by past volcanic activity.

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A global shipping detour just revealed a hidden climate twist

Rerouted shipping during Red Sea conflicts accidentally created a massive real-world experiment, letting scientists study how new low-sulfur marine fuels affect cloud formation. The sudden surge of ships around the Cape of Good Hope revealed that cleaner fuels dramatically weaken the ability of ship emissions to seed bright, reflective clouds—cutting this cloud-boosting effect by about two-thirds.

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A hidden brain energy signal drives depression and anxiety

Scientists discovered that lowered brain energy signaling in the hippocampus can lead to both depression- and anxiety-like behaviors in mice. Stress reduced ATP, a molecule important for cell energy and communication. Altering a protein called connexin 43, which helps release ATP, caused similar symptoms even without stress. Restoring this protein improved mood-related behavior.

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Why did ancient people build massive, mysterious mounds in Louisiana?

Hunter-gatherers at Poverty Point may have built its massive earthworks not under the command of chiefs, but as part of a vast, temporary gathering of egalitarian communities seeking spiritual harmony in a volatile world. New radiocarbon data and reexamined artifacts suggest far-flung travelers met to trade, worship, and participate in rituals designed to appease the forces of nature.

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Scientists find hidden switch that lets tumors shapeshift and evade treatment

Scientists are uncovering what makes some carcinomas so resistant: their ability to change identity. Two new studies reveal crucial proteins and structures that could become targets for future therapies. These discoveries deepen understanding of how tumors reprogram themselves and point toward highly specific treatments. The work raises hopes for safer, more selective cancer drugs.

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How parakeets make new friends in a surprisingly human way

Monk parakeets ease into new friendships, slowly approaching strangers to avoid aggressive encounters. Researchers watched how birds shared space, groomed each other, and escalated to deeper social bonds over time. The results show a clear pattern of cautious exploration echoing similar studies in other animals. Even for birds, making a friend can be a delicate dance.

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A tiny enzyme may hold the key to safer pain relief

Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or sensation. This enzyme, called VLK, modifies nearby proteins in a way that intensifies pain and strengthens connections tied to learning and memory. Removing VLK in mice dramatically reduced post-surgery pain while leaving normal function untouched, offering a promising path toward safer, more targeted pain treatments.

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A tiny enzyme may hold the key to safer pain relief

Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or sensation. This enzyme, called VLK, modifies nearby proteins in a way that intensifies pain and strengthens connections tied to learning and memory. Removing VLK in mice dramatically reduced post-surgery pain while leaving normal function untouched, offering a promising path toward safer, more targeted pain treatments.

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Hidden microglia switch helps protect the brain from Alzheimer’s

Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an outsized ability to keep the brain healthier. When a key signal is removed from them, Alzheimer’s symptoms worsen. This pathway may help explain why some people naturally have reduced Alzheimer’s risk.

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Scientists reveal a hidden hormone switch for learning

Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain how hormonal cycles influence cognitive performance and psychiatric symptoms. This connection offers a new path for understanding brain disorders tied to dopamine.

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Scientists reveal a hidden hormone switch for learning

Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain how hormonal cycles influence cognitive performance and psychiatric symptoms. This connection offers a new path for understanding brain disorders tied to dopamine.

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Tiny microneedle patch dramatically improves heart attack recovery

Researchers created a dissolvable microneedle patch that delivers IL-4 directly to damaged heart tissue, jump-starting repair after a heart attack. The targeted approach shifts immune cells into a healing mode while improving communication between heart muscle and blood vessel cells. It avoids the systemic risks of IL-4 injections and shows promise for future minimally invasive treatment.

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Scientists warn heatwaves will intensify for 1,000 years even after net zero

New climate modeling shows that heatwaves will keep getting hotter, longer, and more frequent for centuries—even after the world hits net-zero emissions. Delays of just a few years dramatically increase the likelihood of extreme, once-rare heat disasters, especially for countries near the equator. The research reveals that even reaching net zero by mid-century won't reverse the trend, and some regions will continue to see worsening heatwaves for a thousand years.

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Blocking a single protein forces cancer cells to self-destruct

Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, with many cancer cells essentially triggering their own self-destruct mode. The work points to a fresh strategy for targeting stubborn lung cancers.

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Scientists reawaken exhausted T cells to supercharge cancer immunity

Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a particular molecular signal to weaken T cells, and that interrupting this signal helps the cells stay active.

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Nanoscale trick makes “dark excitons” glow 300,000 times stronger

Researchers have found a way to make “dark excitons”—normally invisible quantum states of light—shine dramatically brighter by trapping them inside a tiny gold-nanotube optical cavity. This breakthrough boosts their emission 300,000-fold and allows scientists to switch and tune them with unprecedented precision. The work unlocks new possibilities for ultrafast photonics, on-chip quantum communication, and exploring previously unreachable quantum states in 2D materials.

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Supercomputer creates the most realistic virtual brain ever

Researchers have created one of the most detailed virtual mouse cortex simulations ever achieved by combining massive biological datasets with the extraordinary power of Japan’s Fugaku supercomputer. The digital brain behaves like a living system, complete with millions of neurons and tens of billions of synapses, giving scientists the ability to watch diseases like Alzheimer’s or epilepsy unfold step by step. The project opens a new path for studying brain function, tracking how damage spreads across neural circuits, and testing ideas that once required countless experiments on real tissue.

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Supercomputer creates the most realistic virtual brain ever

Researchers have created one of the most detailed virtual mouse cortex simulations ever achieved by combining massive biological datasets with the extraordinary power of Japan’s Fugaku supercomputer. The digital brain behaves like a living system, complete with millions of neurons and tens of billions of synapses, giving scientists the ability to watch diseases like Alzheimer’s or epilepsy unfold step by step. The project opens a new path for studying brain function, tracking how damage spreads across neural circuits, and testing ideas that once required countless experiments on real tissue.

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Secret chemical traces reveal life on Earth 3. 3 billion years ago

Researchers have discovered chemical traces of life in rocks older than 3.3 billion years, offering a rare look at Earth’s earliest biology. By combining advanced chemical methods with artificial intelligence, scientists were able to detect faint molecular patterns left behind long after the original biomolecules disappeared. Newly analyzed fossils, including ancient seaweed from Canada’s Yukon Territory, helped validate the method and deepen understanding of early ecosystems.

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This tiny quantum clock packs a billion-fold energy mystery

Scientists built a tiny clock from single-electron jumps to probe the true energy cost of quantum timekeeping. They discovered that reading the clock’s output requires vastly more energy than the clock uses to function. This measurement process also drives the irreversibility that defines time’s forward direction. The insight could push researchers to rethink how quantum devices handle information.

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Astronomers discover thousands of hidden siblings of the “Seven Sisters”

The “Seven Sisters” have far more relatives than anyone imagined. Using NASA and ESA space telescopes, astronomers found thousands of hidden stars linked to the Pleiades, forming a colossal stellar complex. The discovery expands the cluster’s size by a factor of 20 and offers a new way to trace the shared origins of stars—including our own Sun.

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GLP-1 drugs like Ozempic deliver huge weight loss but new research reveals a hidden catch

GLP-1 drugs like tirzepatide and semaglutide offer powerful weight-loss effects but come with unanswered questions about long-term safety, side effects, and global accessibility. Researchers stress the need for independent studies before these treatments can be fully embraced worldwide.

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GLP-1 drugs like Ozempic deliver huge weight loss but new research reveals a hidden catch

GLP-1 drugs like tirzepatide and semaglutide offer powerful weight-loss effects but come with unanswered questions about long-term safety, side effects, and global accessibility. Researchers stress the need for independent studies before these treatments can be fully embraced worldwide.

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Chimps shock scientists by changing their minds with new evidence

Chimps may revise their beliefs in surprisingly human-like ways. Experiments showed they switched choices when presented with stronger clues, demonstrating flexible reasoning. Computational modeling confirmed these decisions weren’t just instinct. The findings could influence how we think about learning in both children and AI.

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Smoking cannabis with tobacco may disrupt the brain’s “bliss molecule”

Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural feel-good molecule in the brain. This imbalance may help explain why co-users experience more anxiety and struggle more when quitting.

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Extreme floods are slashing global rice yields faster than expected

Scientists discovered that a week of full submergence is enough to kill most rice plants, making flooding a far greater threat than previously understood. Intensifying extreme rainfall events may amplify these losses unless vulnerable regions adopt more resilient rice varieties.

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CRISPR brings back ancient gene that prevents gout and fatty liver

By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human liver models. The breakthrough hints at a future where gout and several metabolic diseases could be prevented at the genetic level.

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CRISPR brings back ancient gene that prevents gout and fatty liver

By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human liver models. The breakthrough hints at a future where gout and several metabolic diseases could be prevented at the genetic level.

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Scientists uncover a hidden limit inside human endurance

Ultra-endurance athletes can push their bodies to extraordinary extremes, but even they run into a hard biological wall. Researchers tracked ultra-runners, cyclists, and triathletes over weeks and months, discovering that no matter how intense the effort, the human body maxes out at about 2.5 times its basal metabolic rate when measured long-term. Short bursts of six or seven times BMR are possible, but the body quickly pulls energy away from other functions to compensate, nudging athletes back toward the ceiling.

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Scientists uncover a hidden limit inside human endurance

Ultra-endurance athletes can push their bodies to extraordinary extremes, but even they run into a hard biological wall. Researchers tracked ultra-runners, cyclists, and triathletes over weeks and months, discovering that no matter how intense the effort, the human body maxes out at about 2.5 times its basal metabolic rate when measured long-term. Short bursts of six or seven times BMR are possible, but the body quickly pulls energy away from other functions to compensate, nudging athletes back toward the ceiling.

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Strange microscopic structures found in Long COVID blood

Scientists have discovered strange microscopic structures in the blood of people with Long COVID—clusters of tiny microclots tangled together with sticky immune webs known as neutrophil extracellular traps, or NETs. These combined structures show up far more often in Long COVID patients, where they appear larger, denser, and more stubborn than in healthy blood.

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Cheap gout drug may slash heart attack and stroke risk

Colchicine, a cheap and widely used gout drug, may help prevent heart attacks and strokes in people with cardiovascular disease. Trials involving nearly 23,000 patients show meaningful reductions in risk with low doses. Side effects were mostly mild and short-lived. Researchers say this overlooked drug could become an accessible prevention tool pending further study.

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Cheap gout drug may slash heart attack and stroke risk

Colchicine, a cheap and widely used gout drug, may help prevent heart attacks and strokes in people with cardiovascular disease. Trials involving nearly 23,000 patients show meaningful reductions in risk with low doses. Side effects were mostly mild and short-lived. Researchers say this overlooked drug could become an accessible prevention tool pending further study.

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Tiny implant wipes out bladder cancer in 82% of patients

TAR-200, a small drug-releasing implant, wiped out tumors in most patients with high-risk bladder cancer. Its slow, consistent release of chemotherapy proved far more effective than traditional short-term treatments. The therapy may replace bladder removal surgery for many and has earned FDA Priority Review due to its impressive results.

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Tiny implant wipes out bladder cancer in 82% of patients

TAR-200, a small drug-releasing implant, wiped out tumors in most patients with high-risk bladder cancer. Its slow, consistent release of chemotherapy proved far more effective than traditional short-term treatments. The therapy may replace bladder removal surgery for many and has earned FDA Priority Review due to its impressive results.

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Running on little sleep? You’re twice as likely to get hurt

Researchers found that runners who sleep poorly face nearly double the injury risk compared to those who rest well. The study highlights that sleep is not just recovery—it’s a key factor in preventing injuries. They stress that runners should prioritize rest alongside training. Simple habits like consistent bedtimes and limiting screens can make a big difference.

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Clearing brain plaques isn’t enough to heal Alzheimer’s

Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to reverse. Their findings underscore that tackling amyloid alone may not be enough to restore brain function, urging a broader approach to treatment.

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Clearing brain plaques isn’t enough to heal Alzheimer’s

Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to reverse. Their findings underscore that tackling amyloid alone may not be enough to restore brain function, urging a broader approach to treatment.

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Doctors found a way to stop a deadly metformin reaction

A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced deaths and sped up treatment times. Awareness also soared, showing how organized emergency pathways can transform patient outcomes.

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Doctors found a way to stop a deadly metformin reaction

A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced deaths and sped up treatment times. Awareness also soared, showing how organized emergency pathways can transform patient outcomes.

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Tiny laser could transform medicine and quantum science

A team at the University of Stuttgart has engineered a compact short-pulse laser that achieves up to 80% efficiency—far surpassing current models. Their new multipass design reuses light within a small crystal, combining power and precision in a palm-sized system. It opens the door to portable, cost-effective lasers for medicine, analytics, and quantum science.

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Stanford makes stem cell transplants safer without chemo

A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells without radiation, enabling nearly complete donor cell replacement. The approach also widens donor eligibility and could soon be applied to other bone marrow failure diseases.

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Stanford makes stem cell transplants safer without chemo

A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells without radiation, enabling nearly complete donor cell replacement. The approach also widens donor eligibility and could soon be applied to other bone marrow failure diseases.

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Common acne drug may protect against schizophrenia

Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the condition as adults. The effect could stem from the drug’s ability to reduce brain inflammation. Researchers say the findings highlight an unexpected new direction in mental health prevention.

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Common acne drug may protect against schizophrenia

Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the condition as adults. The effect could stem from the drug’s ability to reduce brain inflammation. Researchers say the findings highlight an unexpected new direction in mental health prevention.

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Nanotech makes cancer drug 20,000x stronger, without side effects

A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing power while avoiding side effects. This innovation may usher in a new era of precision nanomedicine for cancer and beyond.

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Nanotech makes cancer drug 20,000x stronger, without side effects

A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing power while avoiding side effects. This innovation may usher in a new era of precision nanomedicine for cancer and beyond.

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Scientists shocked to find E. coli spreads as fast as the swine flu

Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, scientists modeled bacterial transmission rates and discovered key differences between strains. Their work offers a new way to monitor and control antibiotic-resistant bacteria in both communities and hospitals.

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Even climate fixes might not save coffee, chocolate, and wine, scientists warn

Even with futuristic geoengineering methods like Stratospheric Aerosol Injection, the fate of wine, coffee, and cacao crops remains uncertain. Scientists found that while this intervention could slightly cool the planet, it cannot stabilize the erratic rainfall and humidity that devastate yields. The findings reveal that only a fraction of major growing regions might benefit, leaving most producers exposed to volatile harvests and economic instability.

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Entangled atoms found to supercharge light emission

Physicists have uncovered how direct atom-atom interactions can amplify superradiance, the collective burst of light from atoms working in sync. By incorporating quantum entanglement into their models, they reveal that these interactions can enhance energy transfer efficiency, offering new design principles for quantum batteries, sensors, and communication systems.

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Scientists achieve forensics’ “Holy Grail” by recovering fingerprints from fired bullets

Researchers at Maynooth University have achieved a forensic milestone by revealing fingerprints on fired bullet casings using a safe electrochemical process. The method uses mild voltage and non-toxic materials to make hidden ridges visible within seconds. Effective even on aged casings, it could help investigators connect evidence directly to a suspect rather than just a weapon.

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Soil microbes remember drought and help plants survive

Researchers discovered that soil microbes in Kansas carry drought “memories” that affect how plants grow and survive. Native plants showed stronger responses to these microbial legacies than crops like corn, hinting at co-evolution over time. Genetic analysis revealed a key gene tied to drought tolerance, potentially guiding biotech efforts to enhance crop resilience. The work connects ecology, genetics, and agriculture in a novel way.

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Scientists find “living fossil” fish hidden in museums for 150 years

Researchers have uncovered dozens of long-misidentified coelacanth fossils in British museums, some overlooked for more than a century. The study reveals that these ancient “living fossils” thrived in tropical seas during the Triassic Period, around 200 million years ago. By re-examining mislabeled bones and using X-ray scans, scientists discovered a once-flourishing community of coelacanths that hunted smaller marine reptiles.

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